Researchers at the Chemical Genomics Center of the Max Planck Society in Munich have promising results from their study of legionella infections. Legionellosis, the process of infection by legionella bacteria, is a particularly evasive infection. The body’s typical immune response involves ‘eating up’ foreign intruders such as bacteria and viruses in a process known as autophagy, ultimately preventing the onset of diseases and infections. A molecule known as LC3-PE is responsible for this process. Legionella bacteria has been found to contain a molecule, called RavZ, that disrupts the actions of LC3-PE and ultimately allows legionella bacteria to propagate within the body,…
According to a lawsuit filed in Manhattan Supreme Court in Early April, four cancer patients staying at the Hope Lodge, an American Cancer Society facility that temporarily houses cancer patients, contracted Legionnaires Disease in early 2015. Of the four cases, Joan Pederson, a 62 year old brain cancer patient was the first and only recorded death associated with the outbreak. Pederson had to stop treatment for her brain cancer for weeks in order to receive treatment for her Legionnaires’ Disease. This outbreak was overshadowed by the much larger, concurrent Bronx outbreaks in which more than 100 people were affected, and…
A suburban Philadelphia high school has been shut down today after legionella bacteria was found in the school’s hot water system. The school was conducting routine testing of their water systems when a water sample from a spigot in the boiler room tested positive for legionella bacteria. This was the only area in the school that tested positive for legionella. The superintendent of the Kennett Consolidated School District, Barry W. Tomasetti, posted a bulletin to the school district’s website informing students and families of these findings. The school district stated that it is working closely with the Chester County Health Department and…
St Elizabeth Medical Center in Utica, New York has found small amounts of legionella bacteria in a handful of sampling locations throughout the campus. The results have been reported to the New York State Department of Health, and the hospital is currently in the process of remediating the presence of legionella. The tests were conducted in accordance with New York state guidelines that require all hospitals within the state to routinely sample their facilities for the presence of legionella. These guidelines were implemented in mid-2016 in response to two deadly outbreaks of Legionnaires’ Disease in the Bronx that took the lives of…
Marc Edwards, a Virginia Tech Civil and Environmental Engineering professor released a selection unpublished results from his team’s study of the 2015 outbreaks of Legionnaires’ Disease that killed 12 people in Flint, Michigan. Edwards, who is most known for sounding the alarm about the dangerous levels of lead in the Flint water system in 2015, believes that the Legionnaires’ Disease outbreak is a result of the water supply switch to the Flint river, coupled with the lack of any application of anti-corrosive and chlorination treatments. To conduct this study, Professor Edwards and his team simulated the outbreak in a lab. Edwards and his…
According to the settlement filings from the ACLU and NRDC’s lawsuit against the City of Flint and the State of Michigan, both defendants are to replace around 18,000 tainted water lines leading to homes from the Flint municipal water supply. The whole operation is expected to cost ninety million dollars and is slated to be completed by 2020. As a result of the disuse of anti-corrosive agents, as well as chlorinated water treatment, these water lines carried not only exceedingly high levels of lead, but legionella bacteria that ended up causing the deaths of 12 Flint residents. More information can be found here…
Chad Grant, the CEO of McLaren Flint Hospital, the facility at the center of the Flint Legionnaires’ Outbreak, released an extremely critical report as a response to a state health department order for the hospital to “correct conditions”. Grant accused state officials of “blaming and attacking” McLaren Flint, and treating it as if it were the sole cause of the Flint outbreak in order to deflect attention from themselves. He referred to the accusations as “unwarranted and unjustified”. Grant points to the Flint municipal water system, which changed its source from Lake Huron to the Flint River, as the driving force behind the…
The VA Pittsburgh Healthcare System has extended water restrictions due to the discovery of Legionella bacteria at its University Drive location. In late January water restrictions were enacted to kill the bacteria in Building 1. Those restrictions have been extended to ensure the water supply has time to sanitize while the sample testing is being repeated. A patient of the Pittsburgh VA was diagnosed with Legionella pneumonia in February and has since been treated. The patient had visited the campus during the 10 day onset of the illness as an outpatient. “At this time, evidence suggests the patient contracted Legionella…
The former director of disease control and prevention at the Michigan Department of Health and Human Services, Corrine Miller, has been sentenced for her involvement in the 2014-2015 outbreak of Legionnaires Disease that killed 12 people in Flint. Corrine Miller admitted to knowing about 100 cases of Legionnaires Disease in the Flint area and failing to report these findings to local hospitals, as well as the general public. Last September, Miller pleaded no contest to a charge of willful neglect of duty, the least serious of the charges filed against her. Miller received 1 year of probation, as well as…
Researchers the Whiting School of Engineering at Johns Hopkins University and Johns Hopkins School of Medicine are currently working on a project to develop single-celled organisms that seek out and kill potentially deadly bacteria. The team was inspired by amoebas that have been known to surround and kill yeast bacteria and develop ‘soldier cells’ out of these amoebas. Using a $5 million dollar grant from DARPA, the Defense Advanced Research Projects Agency, the team is first focusing on making these cells target Legionella and Pseudomonas aeruginosa bacteria. If the project is successful, the possible applications outside of the laboratory are exciting. These amoeba soldiers could be used…